When Can You Give Puppies Their First Shots. In fact, this is how dr schultz says he vaccinated his own puppies. However, regardless of the age of the patient or labeled vaccine duration, the.

When should i get vaccinations done? The idea of a vaccine is to stimulate antibody production from a healthy immune system, so if that is compromised, the vaccine may not only be ineffective, but harmful as well, he adds. Puppies are defined as less than 6 months of age.